Enamine Ltd (est. 1991) is a privately owned chemical company, expert in synthesis of Building Blocks and derived small molecular weight compound libraries for drug discovery needs.
Compound libraries for screening
Enamine's screening collection is the world's largest. It contains over 1.8 million stock compounds, growing by 250 thousand each year. Enamine is the only compound vendor maintaining so efficient synthesis rate. Enamine's screening library is the most reputable and richest source of novel quality drug-like compounds. Diversity of the products and number of the lead-like compounds at Enamine are so impressive (see white papers) that today researchers no longer need to bother with searching multiple catalogues and pay extra for purchasing through brokers.
It is most important for our clients that hits found in our collection can be easily and efficiently followed by resupply of dry samples from stock, by swift supply of numerous analogues, and by synthesis of focused compound libraries. Reagents used for the library synthesis can be purchased from our 50,000 Building Block catalogue which we can complement from the superset of 5 million tangible Building Blocks with only 4 weeks lead time.
Exploring a larger number of compounds allows you to cherry pick the most valuable of them
If you are looking for a pool of compounds to conduct virtual screening we also recommend addition of our database of 16 million tangible compounds to your screening file. The compounds from this database, called REAL database, are synthesized in just one step from already produced and stored on site Building Blocks. The success rate is over 75% and on small selections it often reaches 100% so that compounds can be supplied as if available from stock, with delay of only a couple of weeks. Exploring a larger number of compounds allows you to cherry pick the most valuable of them, and having them delivered from a single prominent supplier helps to save significantly on costs and time.
If you do not have a capacity to screen in-silico huge compound libraries we offer a range of carefully designed and selected compound sets such as: kinase, protease, GPCR, ion channels targeted libraries, diversity sets and fragment libraries. In addition, our specialists can work on a custom library project meeting your specific needs.
Enamine offers on-site biological screening.
50,000 Building Blocks and intermediates for library synthesis and medicinal chemistry
Cost-effective and professional custom synthesis
One of the decisive factors in finding a good partner for outsourcing chemical synthesis is how rapidly a CRO can access required chemicals. We are proud that 90% of necessary chemicals are supplied within 1-2 hours from our on-site inventory.
Enamine has laboratory facilities occupying an area of over 15,000 m2 in Kiev, Ukraine. They are located in several recently constructed buildings, providing state-of-the-art instrumentation, infrastructure and analytical services to over 300 skillful chemists.
We deliver our products through our offices in Europe and USA.
Visit www.enaminestore.com for shopping on-line.