Suzuki reaction has become one of the most powerful synthetic tools in organic chemistry to construct the C(sp²)-C(sp²) bond. Unfortunately, many boronic acids bearing the electron-deficient heterocyclic substituents do not exist. Stannanes are more stable and can also undergo coupling reaction catalyzed with transition metals.
- readily prepared, purified and stored
- compatible with a wide range of functional groups
- mild reaction conditions
- not sensitive to moisture in Stille coupling
>100 Stannanes in gram amounts in stock. Custom synthesis of further analogues and compound libraries
We have designed and synthesized a library of stannanes for coupling reactions, which you can find at MedChem Highlights section of Enamine’s website.