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Tosoh Bioscience

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Tosoh Bioscience

Tosoh Bioscience is an acknowledged global leader in the field of liquid chromatography with a strong focus on bioseparations. We offer solutions for research, drug discovery, clinical chemistry, environmental analysis, manufacturing and other industrial applications.

Tosoh’s portfolio of more than speciality products encompasses a comprehensive line of chromatographic media, high-performance liquid chromatography (HPLC) columns, and gel permeation chromatography (GPC) instruments.

We can help to analyse and purify any protein, peptide, nucleic acid, antibiotic or small molecule.

Based on existing resins, we are also able to develop customised products.

Tosoh Bioscience is the sole sponsor of the conference on Hydrophobic Interaction and Reversed Phase Chromatography (HIC/RPC Bioseparation Conference).

Research for the biopharmaceutical market

Tosoh Bioscience provides research and production of biopharmaceuticals for research institutes, university laboratories and routine laboratories for chemical, biochemical and environmental analysis.

Products for liquid chromotography

Tosoh Bioscience offers a comprehensive line of media and pre-packed columns for all common modes of liquid chromatography, including ion exchange, hydrophobic interaction, reversed phase, size exclusion and affinity.

Toyopearl® and TSKgel® chromatographic resins and columns are renowned for their quality and reliability. In addition to chromatographic resins and columns, Tosoh Bioscience manufactures instruments for GPC.

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Services and facilities

Tosoh Bioscience’s European operations are headquartered in Stuttgart, Germany, and offer technical service by phone, e-mail or on-site.

This service includes troubleshooting, applications for analytical and research and development (R&D) scientists, method development and scale up, as well as on-site large-column packing support.

Tosoh’s manufacturing sites in Japan provide products to the sales and support subsidiaries in the USA, Europe and China, ensuring full global coverage.

Chromatographic techniques

Tosoh uses a wide variety of chromatographic techniques, including:

•  HPLC, ultra-high-performance liquid chromatography (UHPLC) and liquid chromatography-mass spectroscopy ( LC-MS)

•  Ion exchange chromatography (IEC)

•  Hydrophobic interaction chromatography (HIC)

•  Reversed phase chromatography (RPC)

•  Hydrophilic interaction chromatography (HILIC)

•  Size exclusion chromatography (SEC) and high-pressure size exclusion chromatography (HPSEC)

•  Gel permeation chromatography (GPC)

•  Affinity chromatography

•  Preparative and process chromatography

Contact details:
Tosoh Bioscience GmbH

Im Leuschnerpark 4
64347 Griesheim
Germany
Tel: +49 6155-7043700
Fax: +49 6155-8357900
info.tbg@tosoh.com
www.tosohbioscience.de

HPLC Columns

TSKgel® stationary phases are available as porous or non-porous, silica or polymeric particles (2-10 µm) in HPLC columns for micro-bore, analytical or preparative use.

The development of the first TSKgel GPC column in 1971 had set the course for a long and proud history of size exclusion chromatography (SEC) at Tosoh. Today, the range of SEC related products comprises of SEC/GPC systems and stationary phases for both modes of size exclusion chromatography, aqueous gel filtration (GFC) and organic gel…

Preparative and Process Chromatography

TOYOPEARL® and TSKgel® resins are based on a semi rigid, hydrophilic, macroporous particle. Their rigid backbone has better pressure-flow properties than most other commercially made materials.

Therefore, higher linear operating velocities can be used for faster process throughput and decreased recycling times. TOYOPEARL resins are stable over the pH 2-12 range for normal operating conditions and pH 1-13 for cleaning conditions. They are available in average particle sizes of 35, 65, 75, and 100 µm for high resolution, intermediate purification, or…

SEC/GPC Instruments

Based on a long history of producing GPC/SEC systems for the Asian market, Tosoh developed the EcoSEC system to meet the market needs for high resolution, semi micro GPC. EcoSEC is a compact, all-in-one GPC system.

It offers outstanding performance and short analysis time when combined with semi-micro columns. Semi-micro GPC saves solvent, sample amount, analysis time and waste disposal costs.
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Tosoh Bioscience Releases New Hydroxyapatite with Ca++Pure-HA

Tosoh Bioscience has introduced a new hydroxyapatite medium to its product portfolio.
11th October 2018

Tosoh Bioscience: New High Capacity TOYOPEARL® rProtein L Resin

High capacity chromatography resin for the capture of antibodies and antibody fragments.
31st July 2017

Tosoh Bioscience: Broad Dynamic Range for Fast Antibody Titer Analysis

TSKgel Protein A-5PW supports high throughput screening by fast analysis.
31st July 2017

TSKgel Size Exclusion Columns for UHPLC

Increased throughput and resolution for SEC analysis
15th November 2016

TOYOPEARL Sulfate-650F – The Smart Cation Exchange Resin

Salt tolerant cation exchanger with high IgG capacity
15th November 2016

Tosoh to Increase Production Capacity of Toyopearl Liquid Chromatography Separation and Purification Media

Tokyo, Japan —Tosoh Corporation has announced that it will be increasing the production capacity of its Toyopearl liquid chromatography separation...
24th October 2016

New Ultra-High Capacity TOYOPEARL® Protein A Resin

High capacity chromatography resin for the capture and purification of monoclonal antibodies.
16th December 2013

TSKgel mAb SEC Columns – Setting new Benchmarks for Antibody Analysis

TSKgel SW size exclusion columns - the industry's workhorse for aggregate analysis - continue to set standards for the UHPLC...
5th June 2013

TSKgel Protein C4-300: Speed and Resolution for Proteins Analysis

Tosoh Bioscience introduces a new reversed phase HPLC column for the separation of intact proteins. TSKgel Protein C4-300 consists of...
27th March 2012
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