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SIRION BIOTECH

SIRION BIOTECH specialises in viral vector platforms and provides sophisticated cell modelling, which enables a highly improved target identification and compound screening in the drug, food and cosmetic industries

Sophisticated technology for improved cell models

The technology leader in the field of functional gene analysis and cell models for early research has built a sophisticated technology platform consisting of:

  • Viral vectors (Adenovirus, Lentivirus, Adeno-Associated Virus)
  • Advanced siRNA-validation technology (RNAiONE™) for knockdowns of nearly 100%.

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Cells by Design™

SIRION BIOTECH offers Cells by Design™ that come as:

  • Customized in vitro cell models
  • SenCELL™cell lines with built-in reporter genes, e.g. Hypoxia or sensory taste cells

Primary Cell Immortalizations, 3D Cell Cultures & Adenovirus Serotypes as Vaccines

SIRION BIOTECH’S specialisation in this field allows for greater chances of success with primary cell immortalisations. Only with such specialization is it possible to construct adenovirus serotype vectors which may serve as the basis for novel future vaccines with improved immunity.

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Multiple ways exist to work with SIRION BIOTECH ranging from

  • Fee for Service as part of a MasterService Agreements – typical for custom viruses or shRNA validation
  • Exclusive rights on single clones in cases of customised in vitro cell models – typical for tailor made cell models, immortalisation services or 3D cell models
  • Joint development at cost plus and agreed upon milestones and royalties, typically for new in vitro systems and new adenovirus serotypes

Changing the paradigm of in vitro cell modelling

Founded in 2006 by scientists from Munich University (LMU) the idea behind SIRION BIOTECH was to change the paradigm of in vitro cell modelling for more effective target & compound research. Since then, SIRION BIOTECH has been filing several patent applications and has been refining its technical competence in hundreds of client projects. Clients and Alliance Partners range from across Europe, Japan and the U.S.

Contact

SIRION BIOTECH
Am Klopferspitz 19
D-82152 Martinsried near Munich
Germany
Tel:+49 89 700 961 99 13
Fax: 49 (0) 89 700 961 99 8
Email: info@sirion-biotech.de
URL:www.sirion-biotech.com

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AdenoONE™

Everything you need to work successfully with adenovirus

The secret to successful and highly potent virus preparations are:A patent pending adenovirus vector technology combined withLong standing expertise and practical experience in virus purification and concentration.The brand new product line under the....AdenoONE™ is meant to make SIRION BIOTECH's longstanding expertise easily available to our customers.Experience high quality adenoviruses in your own lab.The AdenoONE™ product…

RNAiONE™

SIRION BIOTECH is celebrating first applications of nearly 100% inducible knockdowns. What was considered impossible only a few years ago, is now becoming an industry standard.

Inducible Knockdowns of nearly 100%!? - Is that possible?Conditional gene silencing is what the researcher wishes to show. Towards that goal, limited dilution helps generating clonal cell lines from the stable pool. Subsequent quantification of target gene X in 25 Dox-treated clones then showed significant variations in mRNA expression levels.PrincipleCloning of the cDNA of Your…

SenCELL™

Identification of next generation active compounds is a critical step in drug and related compound discovery.

New! - Sensor Cell lines for drug discoverySenCELL LifeAct™ represents a range of First in Class Sensor Cell Lines:Sensor molecules identify actin or hypoxia dynamicsNo interference with dynamic processes during cytoskeleton rearrangementsSenCELL LifeActTM express a small actin binding protein domain coupled to a fluorescent protein.Suited for live cell imaging and high content analysis,Applicable to a…

Tailor Made Clonal Cell Lines

Custom cell lines created and modified with an expression vector of your choice with optimal transgene expression, guaranteed stability, reliable cell banking and ready-to-use in just 4-6 weeks.

Service ComprisesTransfection/transduction of Your Cell Line with an expression vector of your choiceGeneration of stable cell pools by antibiotic selection.Establishment of single cell clones using the Genetix Clone Select ImagerSmall scale expansion of individual clonesIdentification of "High Performers" via quantification of target gene or GOI expression by qRT-PCR and/or Western Blot relative to control cellsLarge…
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Quick Contact SIRION BIOTECH
Quick Contact SIRION BIOTECH
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