Next Generation Sequence Analysis (NGS)

Fios Genomics offers a comprehensive range of services for the analysis of data from the latest Next Generation Sequence (NGS) technologies. NGS enables an individual’s entire genome to be assessed for transcriptomes or the level of variation (polymorphism). Genome-wide association studies (GWAS), SNP detection and haplotype analysis using NGS approaches can facilitate the discovery and typing of novel SNPs implicated in disease or response to drugs. Our services incorporate expert knowledge with advanced computing to enable efficient processing and analysis of large and complex datasets.

We can process NGS data from all the major technology platforms (Illumina, SOLiD, 454) for a wide range of applications:

• RNA-seq: whole transcriptome sequencing for differential gene expression analysis
• Exome analysis: for identification of known and novel SNPs and indels
• Genome-wide association studies (GWAS): to facilitate discovery of SNPs implicated in disease
• ChIP-seq: analysis of DNA-protein interactions
• Methyl-seq: bisulfite sequencing for epigenetic studies