Production & SalesMarketing & Sales December 24, 2020 Pfizer, BioNTech agree to supply additional 100 million Covid-19 vaccine doses to US By PBR Staff Writer With the latest deal, the companies now will deliver up to 200 million doses to the US. Both firms plan to supply the full 200 million doses to
RegulationDrug Filing December 23, 2020 FDA accepts Hepion’s IND application for CRV431 to treat Covid-19 By PBR Staff Writer In July this year, the company revealed a potential two-pronged strategy for the treatment of Covid-19. First, preclinical cell culture experiments shown CRV431 reduced SARS-CoV-1 production of infectious
Drug DiscoveryResearch & Development December 22, 2020 Servier to buy Agios’ oncology business for up to $2bn By PBR Staff Writer The deal, which covers commercial, clinical and research-stage oncology portfolio, consists of an upfront payment of $1.8bn. Agios is also eligible to secure up to $200m in regulatory
RegulationApprovals December 21, 2020 Moderna gets FDA EUA for Covid-19 vaccine candidate mRNA-1273 By PBR Staff Writer As per the EUA, the mRNA-1273 vaccine can be administered to individuals aged 18 years or older. Following the EUA, Moderna has commenced delivery of the Covid-19 vaccine
RegulationApprovals December 18, 2020 GSK gets FDA nod for Benlysta to treat adult patients with active lupus nephritis By PBR Staff Writer Lupus nephritis, an inflammation of the kidneys caused by systemic lupus erythematosus (SLE), may lead to end-stage kidney disease. Benlysta, a BLyS-specific inhibitor, is a human monoclonal antibody
Drug DiscoveryResearch & Development December 17, 2020 Novartis to buy neuroscience firm Cadent Therapeutics for up to $770m By PBR Staff Writer Based in Cambridge of Massachusetts, Cadent Therapeutics is involved in the development of therapies to treat cognitive, mood, and movement disorders. Cadent will secure a $210m upfront payment,
Clinical TrialsPatient Enrollment December 16, 2020 FSD Pharma doses first patient in phase 2 Covid-19 trial of FSD201 By PBR Staff Writer The randomised, controlled and double-blind study will recruit 352 patients in between 25 and 30 medical centres and hospitals in North America. The multicentre study will evaluate the
RegulationApprovals December 15, 2020 Acceleron gets EC orphan designation for sotatercept to treat PAH By PBR Staff Writer PAH is a rare and chronic progressing disorder characterised by the narrowing of small pulmonary arteries and inflated blood pressure in the pulmonary circulation. Sotatercept, an investigational reverse-remodelling
Drug DiscoveryResearch & Development December 15, 2020 EQT IX offers to buy Swedish firm Recipharm for $2.1bn By PBR Staff Writer Via newly established Swedish limited liability company Roar BidCo AB, EQT IX has announced a public offer of SEK220 ($26.1) in cash per share to the shareholders of
RegulationApprovals December 14, 2020 Novartis gets EC nod for Leqvio to treat hypercholesterolemia or mixed dyslipidemia By PBR Staff Writer Leqvio, a first-in-class small interfering RNA (siRNA), has been approved based on data from the ORION clinical development programme. The approval allows to use Leqvio in combination with