RegulationApprovals January 17, 2022 US FDA approves Pfizer’s Cibinqo for atopic dermatitis treatment By PBR Staff Writer The latest move follows the receipt of European Commission (EC) approval for the drug in December last year. Cibinqo, the oral small molecule drug, selectively hinders Janus kinase
Drug DiscoveryResearch & Development January 14, 2022 Prellis, Bristol Myers Squibb collaborate to discover antibodies By PBR Staff Writer As part of the collaboration, the companies will use Prellis Biologics’ externalised human immune system (EXIS) which is based on human lymph node organoids (LNO). The human antibody
Drug DiscoveryResearch & Development January 13, 2022 Lantern Pharma and NCI expand oncology partnership By PBR Staff Writer The latest move follows the identification of various gene signatures that predict a tumour’s possible response to these drug candidates of Lantern. LP-184 is being analysed as a
Oncology January 12, 2022 Neogene Therapeutics signs global license agreement with NCI for cancer treatment By PBR Staff Writer The laboratory of Steven Rosenberg, chief of surgery at the NCI, discovered these TCRs. NCI is an institute of the National Institutes of Health (NIH). Neogene’s neoantigen TCR
Neurology January 11, 2022 Pfizer, Beam sign multi-target research collaboration for rare diseases By PBR Staff Writer The collaboration will see the base editing programmes to be evaluated leverage Beam’s in vivo delivery technologies. These technologies use messenger RNA (mRNA) and lipid nanoparticles (LNP) to
Drug DiscoveryResearch & Development January 7, 2022 Amgen, Generate Biomedicines partner to create protein therapeutics By PBR Staff Writer The partnership aims to develop new drugs with predictable manufacturing and clinical behaviour. Under the deal, Amgen will make an upfront investment of $50m for the first five
Research & DevelopmentDrug Manufacturing January 4, 2022 Ovid signs license deal with AstraZeneca to expand epilepsy drug pipeline By PBR Staff Writer The agreement also includes the lead candidate, OV350, which showed promising in-vitro and in-vivo proof of concept in resistant forms of epilepsy. The early-stage compound directly targets and
Drug Manufacturing December 29, 2021 Texas Children’s Hospital to launch protein sub-unit Covid-19 vaccine By PBR Staff Writer The move comes after the Drugs Controller General of India (DCGI) granted emergency use authorization (EUA) for the vaccine, dubbed ‘The World’s COVID-19 Vaccine’. Corbevax technology was engineered
Drug Delivery December 23, 2021 Merck, Ridgeback to supply 1.75 million molnupiravir courses to UK By PBR Staff Writer Molnupiravir is an orally administered form of a potent ribonucleoside analogue that blocks the SARS-CoV-2 replication. It is planned to be sold under the trademark Lagevrio in the
RegulationApprovals December 21, 2021 EMA’s CHMP recommends approval for AstraZeneca’s Saphnelo to treat SLE By PBR Staff Writer A fully human monoclonal antibody, Saphnelo targets subunit 1 of the type one interferon (type 1 IFN) receptor, blocking the type 1 IFN’s activity. It has been recommended