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Spesolimab has been developed to block the interleukin-36 receptor (IL-36R) activation. IL-36R is a signalling pathway in the immune system that is involved in the pathogenesis of many

The latest move follows a definitive agreement signed by the companies on 21 November this year. Merck stated that the tender offer will expire on 10 January next

Nitrase Therapeutics is deploying its NITROME platform for developing several therapies that target nitrases, a new enzymes class discovered by the company. The platform has created leads for

PreHevbrio has been approved for active immunisation against infection which is caused by all known subtypes of HBV in people aged 18 years and above. It is said

The designation will potentially facilitate the development and accelerate new therapies review for treating serious conditions which have unmet medical need. Moleculin noted that the company is now

Hummingbird Bioscience utilises its technologies to drug clinically-validated targets that have earlier been elusive. Its advanced programme, HMBD-001, is a HER3 antibody that targets an epitope on the

Darovasertib is a potential first-in-class protein kinase C (PKC) inhibitor, and crizotinib is an investigational cMET inhibitor. The designation will allow the darovasertib / crizotinib development programme to

With a differentiated mechanism of action, momelotinib has inhibitory ability along three important signalling pathways, Janus kinase (JAK) 1, and JAK2 and activin A receptor type I (ACVR1).

The multi-target, multi-year partnership will combine the clinical and commercial knowledge of Rallybio in rare diseases with AbCellera’s antibody discovery engine for identifying optimal clinical candidates and providing