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In the current study, radiation of glioma xenografts led to induction of hypoxia-inducible factor (HIF)-1 as measured in vivo by HIF-1 dependent PET imaging. PX-478 inhibited this induction

The study showed that in a mouse model of hormone-refractory prostate cancer, the combination of the bavituximab equivalent antibody 2aG4 and the chemotherapy drug docetaxel significantly decreased the

The combination of Tumor Targeted Superantigens (TTS) and Taxotere significantly improved anti-tumor activity compared to the respective mono therapy. Furthermore, combining TTS and Taxotere synergistically prolonged long-term survival

Virtual Radiologic expects the acquisition to contribute between $3 million and $3.5 million in annual revenue during 2008, and to contribute between $4 million and $4.5 million in

The FDA approval of Patanase nasal spray was based primarily on multiple clinical studies for the evaluation of safety, efficacy and onset of action. The results of these

Under the agreement, SynCo will fill and finish batches of OncoMed’s lead product, antibody OMP-21M18, for use in Phase I clinical trials. SynCo will fill and finish antibody

The study suggests that, while brostallicin is more effective in cells with normal p53 status, cells with abnormal or missing p53 are also killed when treated. P53 is

Following the effective date of termination of the co-promotion agreement there will be no continuing financial commitments for either company, and Santarus will no longer be obligated to

One of the studies is a Phase II clinical trial to assess the potential of the anti-IL-13 monoclonal antibody (MAb) in patients with uncontrolled asthma despite optimal treatment.