Peptisyntha is a leading cGMP manufacturer of therapeutic peptides (peptide APIs) and peptidomimetics serving customers of the pharmaceutical, biotech, diagnostic and cosmetic industries.
From process development for a few milligrams to the manufacturing of several hundred kilograms of peptides, Peptisyntha has strong track records in providing scale-up under full cGMP conditions. The company which was founded in 1987 is proud of having successfully developed processes to supply several 100’s of kilograms of challenging peptide sequences. With more than 23 years of experience in peptide manufacturing, Peptisyntha provides a seamless portfolio of expertise from lead optimization to commercial cGMP manufacturing.
Peptisyntha possesses state-of-the-art equipments to efficiently cover the manufacture of diverse volumes of peptide APIs by:
Our team of experts will design the most efficient process for your API. Innovative LPPS technologies such as persilyation, handling of arginine-rich peptides, synthesis of short peptides without HPLC purification, peptides with multiple disulfide bridges or conjugations allow cost effective processes by reducing the number of chemical steps and increasing yields.
For SPPS Peptisyntha has, for instance, extensive experience both in Fmoc and Boc strategies and has successfully produced peptides with more than 100 residues. Last but not least, Peptisyntha offers hybrid strategies by designing best fragment strategies by coupling either in solution or on solid support to achieve the highest crude purity and avoiding extensive HPLC purification.
Our performance is a result of sound expertise in process chemistry and analytics combined with innovative solutions and custom services. This yields to short delivery times and excellence in cost effective processes. In addition to that, a range of patented technologies guarantee that your project benefits from our competitive advantage.
The Peptisyntha teams in Brussels (Belgium) and Torrance (California, USA) are following a strong and long-term commitment to the highest standards. These ambitions are reflected by regular and successful FDA (no form 483) and EMEA inspections of our state of the art facilities.
Furthermore, by providing outstanding quality assurance and regulatory support, Peptisyntha underlines its dedication for its customers. Your product deserves the best regulatory support possible. During every single step in your product development, Peptisyntha will have a team of regulatory and quality experts at your disposal to support you.
The set of our capabilities enable us to meet your project needs and to serve you with innovation, performance and dedication – for ‘Your Chemistry for Life.’
In brief, Peptisyntha serves you with: