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Boehringer Ingelheim

Drug Substance and Drug Product Services

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March 8, 2012

Boehringer Ingelheim Launches ‘Lean-to-Clinic’ Program for Fast Drug Product Supply

Boehringer Ingelheim has expanded its biopharmaceutical cell line development services and provides drug substance as fast as 13 months at...
pharmacuetical business review


Boehringer Ingelheim

Boehringer Ingelheim is one of the world’s 20 leading pharmaceutical companies. Headquartered in Ingelheim, Germany, it operates globally with 145 affiliates in 50 countries and more than 42,000 employees. Since it was founded in 1885, the family-owned company has been committed for 125 years to researching, developing, manufacturing and marketing novel products of high therapeutic value for human and veterinary medicine.

Services for pre-clinical development

Today, Boehringer Ingelheim is one of the world’s leading companies for contract development and manufacture of biopharmaceuticals. All types of services from mammalian cell line or microbial strain development to final drug production can be delivered within a one-stop-shop concept.

Boehringer Ingelheim delivers services for pre-clinical development up to global market supply with a strong commitment to its customers at its manufacturing facilities for mammalian cell culture and microbial fermentation. Boehringer Ingelheim has brought 19 molecules to market and has many years of experience in multiple molecule classes such as monoclonal antibodies, recombinant proteins, interferons, enzymes, fusion molecules and plasmid DNA. Furthermore, high-titer platform technologies for new antibody mimetic formats such as scaffold proteins and antibody fragments are available for the manufacture of customer products.

Boehringer Ingelheim offers the entire production technology chain at its biopharmaceutical manufacturing facilities in Vienna (Austria), Biberach (Germany) and Fremont (USA). It has the world’s largest capacities for contract development and manufacturing of mammalian cell culture products and is one of the leading manufacturers of biopharmaceuticals.

Boehringer Ingelheim’s experience: Process development (including proprietary high-expression systems in CHO, E.coli and Yeasts) and manufacturing of biopharmaceuticals such as therapeutic proteins, monoclonal antibodies, antibody fragments, protein scaffolds, and plasmid DNA for clinical trials and global market supply.

BOEHRINGER INGELHEIM’S SERVICES in biopharmaceuticals manufacturing include:

Mammalian Cell Culture

  • Clinical material capacities: flexible scales from 80 to 2,000 L
  • Production capacities: flexible scales from 2,000 L to 15,000 L
  • Batch, Fed-batch and perfusion operations

Microorganisms Fermentation

Clinical material capacities: flexible scales from 30 to 6,000 L
Production capacities: flexible scales from 300 L to 6,000 L
Batch or fed-batch fermentation

Downstream Processing

  • Multi-product purification suites
  • Explosion-proof unit and preparative HPLC
  • Viral inactivation procedures

Pharmaceutical Manufacturing

  • Up to 150,000 vials per batch aseptic filling
  • Up to 100,000 syringes per batch aseptic filling
  • Up to 150,000 cartridges per batch aseptic filling

Opportunities for Boehringer Ingelheim’s partners

  • One-stop-shop from DNA to final dosage form
  • Project start without initial investment at every step in the value chain
  • Global supply of biopharmaceuticals up to large and commercial quantities
  • Worldwide-licensed multi-product facilities


Boehringer Ingelheim Pharma GmbH & Co. KG
Binger Strasse 173
55216 Ingelheim

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Animal Health

Vetmedica, the animal health division of Boehringer Ingelheim was founded in the 1950s, and established a UK presence in 1980, initially focussing on equine respiratory disease. Since that time, Vetmedica has expanded to be the 8th largest veterinary pharmaceutical company in the UK, is also one of the fastest growing (with an average annual turnover growth of 16% per year since 1999. Vetmedica is also the fastest growing division in the Boehringer UK business.

Vetmedica promotes a wide range of both therapeutic and preventative products, dealing with both companion animals (dogs, cats, rabbits and horses) and farm animals. All Vetmedica products are sold through veterinary surgeons in the UK. We currently have no direct consumer healthcare presence. For all enquiries regarding veterinary information in the UK, please contact us…

Consumer Health Care

A growing force in the UK Consumer Health Care market, amongst some of the leading brands in the natural health and gastro-intestinal categories.

The Pharmaton® natural health range Pharmaton® For the relief of daily fatigue. A natural health medicine containing unique Ginseng G115, vitamins and minerals. Pharmaton® is available in most pharmacies, grocery and health food stores. To find out more about Pharmaton® visit Antistax® A natural health supplement to help avoid aching, heavy and tired legs.…

Prescription Medicine Brands

We have a reputation for providing effective products for the treatment of chronic obstructive pulmonary disease (COPD), heart attack, secondary stroke prevention and treatment, high blood pressure, thromboembolic disease, HIV/AIDS, Parkinson's disease, arthritis and pain relief in cancer.

For a list of products, a summary of their characterisitics and patient information leaflets, please click here.
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