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Animascope

Preclinical Imaging Services

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Animascope

Animascope is a company providing multimodality imaging services to international customers. Animascope experts have several years of experience in discovery and preclinical imaging in vivo.

Preclinical imaging technologies support the development of innovative diagnostic, prognostic and therapeutic applications. Noninvasive in vivo imaging technologies play a crucial role in understanding the underlying physiopathology of human diseases through real-time acquisition, processing and quantification of whole-body images.

Preclinical imaging studies are therefore of great interest for the development of new pharmaceuticals through the use of a broad range of existing methodologies and the development of new diagnostic and therapeutic options for the management of pathologies.

Non-invasive in vivo imaging

In biomedical research, non-invasive in vivo imaging is applicable to exploratory research and bridges the gap between preclinical and clinical research. In R&D, imaging is particularly useful for pathophysiology, drug efficacy evaluation and model validation studies. In contrast to the conventional ex vivo techniques (i.e. immunohistological techniques), in vivo imaging techniques are non-invasive and can therefore be used to perform longitudinal and dynamic studies. Indeed, the use of these tools minimises the intra- and interspecies experimental variability, greatly reduces the need for an elevated number of animals, and curtails the time to perform a given experiment. Non-invasive in vivo imaging is a cost and time-effective approach to streamline R&D and increase predictability of clinical outcomes.

Preclinical medical imaging

Preclinical medical imaging is applicable to dynamic distribution and biomarker validation studies, and assessment of the delivery, liberation, efficacy and safety of drugs, biologics, biopharmaceuticals, nanoparticles, biomaterials and stem/progenitor cells.

Neuroimaging

New imaging technologies will ultimately contribute to identify important biomarkers and surrogate endpoints both for preclinical and clinical research. For instance, neuroimaging is now central to research and drug development in the neurosciences since it can be used to detect the pharmacological and physiological consequences of drug action within the living brain. Imaging is also essential to diagnose cancers. However this technology is not only useful to detect and localise the tumours, it is also a fundamental instrument to determine the progression and evolution of cancer and response to treatment.

Because a single modality cannot answer all questions, a multimodal approach is crucial. With multi-modality imaging, multiple experimental readouts (anatomy, biodistribution, efficacy, safety and kinetics) are available within the frame of the same study, in the same anatomical context.

Biomedical 3D imaging

Multidisciplinary expertise and several years of practice are required to develop effective capabilities in non-invasive biomedical 3D imaging exploratory research. In this context, Animascope was founded to provide state-of-the-art multimodality imaging services to international customers: optical imaging, ultrasound imaging (US), X-ray computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT) and such as magnetic resonance imaging (MRI).

Animascope services bring ethical and cost advantages to your study and help you save a significant amount of time in the R&D process, accelerating the transfer of a potential new drug from the preclinical stage to the market. To find out more, visit www.animascope.euand give your study a new look.

Animascope
ZA Eurekalp
38660 Saint-Vincent-de-Mercuze
France

Tel: +33 (0) 476 979 487
d.christiaen@animascope.eu
www.animascope.eu

CardioImaging

Non-invasive imaging has revolutionised the diagnosis of the most common cardiovascular diseases. At Animascope, state-of-the-art technologies are used to support the development of new methods of diagnostics, prognostic, and therapeutic efficacy evaluation for newly developed treatments.

We offer preclinical imaging services in an ethical and technical environment which allow our specialized teams to exploit a dedicated small animal imaging platform and to produce reproducible and reliable results for small studies as well as large cohorts being studied longitudinally. Nuclear imaging and cardiology Nuclear imaging is used to detect in a noninvasive…

EcoTox

Risk assessment in ecotoxicology relies on the evaluatıon of the probability of being exposed to a pollutant and on the evaluatıon of the biological impact of such an exposure.

In vivo tesıng is the definitıve accepted method to evaluate the risks. These tests require the use of large number of animals, and are therefore linked to ethical (animal usage) and economical (high costs, tıme-consuming) consequences. Ideally, toxicological studies' design should have a strong and positive impact on the three Rs (reduce, refine, replace). Quantitative,…

In Vivo Optical Imaging

Animascope uses state-of-the-art imaging technologies to support the development of innovative diagnostic, prognostic and therapeutic applications. In vivo imaging has become a cornerstone in clinical and preclinical studies.

Noninvasive technologies facilitate the studies of structures, functions and dysfunctions of organs through real-time acquisition, processing and quantification of whole-body images. In biomedical research, in vivo imaging is applicable to exploratory research, and bridges the gap between preclinical and clinical research. Imaging is particularly useful for pathophysiology, phenotyping and model validation studies. Non-invasive in vivo…

NeuroImaging

MRI has the capability of studying live organisms without exposing them to potentially harmful ionizing radiation. Besides anatomical imaging, MRI is also capable of providing physiological information about several important aspects of biological processes.

The MRI has established itself as an important clinical tool in the diagnosis of central nervous system diseases. For example, the complete imaging evaluation of CNS neoplasms includes detection, characterisation, and determination of tumour extent (or metastatic spread). To see the complete technical file for neuroimaging, please click here.

OncoImaging

Imaging is essential to diagnose cancers. However this technology is not only useful to detect and localise the tumours, it is also a fundamental instrument to determine the progression and evolution of cancer and response to treatment.

At Animascope, state-of-the-art technologies are used to support the development of new methods of cancer diagnostics, prognostic, and therapeutic efficacy evaluation for newly developed treatments. Animascope provides additional services such as training and consultancy, model selection and sourcing, allowing to accelerate the drug development process for unmet needs related with human diseases (cancers), image analysis,…
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