OnKure, a leader in discovery and development of next generation histone deacetylase (HDAC) inhibitors, entered into a clinical trial collaboration and supply agreement with Pfizer to support the clinical proof of concept study for MEKTOVI (binimetinib) in combination with OKI-179, a highly potent and tolerable Class I HDAC inhibitor currently in Phase I for the treatment of NRAS melanoma.
Swiss drugmaker Roche has completed a share purchase agreement to acquire an Irish biotechnology company Inflazome for an upfront payment of €380m.
AstraZeneca has acquired a preclinical oral PCSK9 inhibitor programme from Dogma Therapeutics for an undisclosed price.
Moderna, a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients and Chiesi Farmaceutici S.p.A., an international research-focused healthcare group (Chiesi Group), announced a collaboration aimed at the discovery and development of mRNA therapeutics for the treatment of pulmonary arterial hypertension (PAH), a rare disease with an incidence of 2-5 per million adults.
Takeda Pharmaceutical has opened a new 24,000ft² research and development (R&D) therapy manufacturing facility in Massachusetts, US.
HiFiBiO Therapeutics has entered into a partnership with South Korea-based ABL Bio to co-develop its SARS-CoV-2 neutralising antibody HFB30132A for the treatment of Covid-19.
Drug-maker Merck has announced the acquisition of a $1bn equity stake in biotechnology company Seattle Genetics.
Gilead Sciences has agreed to acquire Immunomedics, a US biopharma company engaged in the development of antibody-drug conjugates (ADCs) for cancer, in a deal worth around $21bn.
Exelixis and NBE-Therapeutics announced a partnership to discover and develop multiple antibody-drug conjugates (ADCs) for oncology applications by leveraging NBE’s unique expertise and proprietary platforms in ADC discovery, including site-specific conjugation and novel payloads.
Cycle Pharmaceuticals, a privately-owned, global, patient-dedicated biotechnology company focused on developing and delivering medicines for rare diseases, today announced that it has executed a definitive agreement for a $25 million credit facility with Deutsche Bank AG.
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