Developing elastomeric components for prefilled syringes is no easy task. The high demands on compound compatibility and functional performance require the most advanced formulations and designs. As always, Helvoet Pharma is up to the task.
|Components for prefilled syringes must perform a variety of functions. Plungers, for instance, must not only ensure a perfect plunger barrel seal integrity (PBSI) but must also demonstrate perfect gliding behaviour in order to administer the syringe contents safely and consistently, even after several years of storage.|
Tip caps and needle shields, on the other hand, must not only form a tight seal but also enable the adequate sterilisation of semi-assembled syringe systems. The permanent contact between the contents and elastomeric components also places extra demands on the compound’s E&L profile.
Helvoet Pharma employs the most advanced formulations based on halobutyl elastomers to meet the multiple challenges of prefilled syringe components. Helvoet Pharma components are lubricated with silicon oil to ensure good machineability, prevent sticking in bulk packaging and guarantee good gliding behaviour once assembled in the barrel. For silicon oil-sensitive applications, Helvoet Pharma components are also available with a fluoropolymer coating. This specialised coating eliminates the need for siliconisation while also creating a robust barrier between the drug and the rubber, thus minimizing extractables and leachables even further.
As always, Helvoet Pharma’s experienced professionals are at your full disposal for obligation-free advice on choosing the right components for optimum safety, convenience and cost-effectiveness. Our prefilled syringe components are available in a variety of packaging formats from bulk to RfS and RTU to ensure the maximum flexibility and efficiency of your supply chain.