Safety First: Tosoh Bioscience Transforms Gene Therapy with Innovative AAV Analysis Technique
Tosoh Bioscience, a renowned leader in the field of chromatography, announced the recent publication of a groundbreaking paper titled 'Separation of Full and Empty AAV Capsids by Anion-Exchange Chromatography Using Choline-Type Salts'. The research, made accessible to the scientific community through SSRN/Elsevier as a pre-print publication, spotlights an innovative analytical method for professionals working with adeno-associated viruses (AAVs) that ensures a safer working environment and environmental protection. The method uses non-toxic choline chloride for the separation of empty and full AAV capsids, marking a significant improvement in comparison with the traditionally used, and highly toxic, tetramethylammonium chloride (TMAC).
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