Reaction Biology gets NIH grant for bromodomain research
The grant will help fund an examination of the interaction of over 1400 FDA-Approved drugs and drug-like compounds with a variety of bromodomains, and facilitate the creation of
The European Medicines Agency (EMA) and the US Food and Drug Administration (FDA) have granted paediatric clinical trial waivers to Shanton Pharma for its lead candidate SAP-001, easing the drug’s regulatory paths to approval.
This patent, with a priority date of 2008, covers screening mechanisms for identification of small molecules that can modulate the function of a nuclear receptor target that was
After the respective agreement, both Proteus and Boston Children’s Hospital will remain as key members of the collaboration steering committee. The agreement includes about $85m in upfront and
The results showed patients with relapsed/refractory CLL taking venetoclax in combination with rituximab, had an overall response rate (ORR) of 84%. In addition, six patients stopped venetoclax after