Syndax, Ventana to devise companion diagnostic test for Entinostat
Entinostat is a novel, oral small molecule inhibitor of class I histone deacetylases, key enzymes that alter the structure of chromatin to control gene expression. Data from Encore
The US Food and Drug Administration (FDA) has issued traditional approval to Novartis for Fabhalta (iptacopan), to slow the decline of kidney function in adults with primary immunoglobulin A nephropathy (IgAN) who are at risk of disease progression.
EGP-437 is formulated for delivery using the EyeGate II drug delivery system, a non-invasive iontophoretic drug delivery technology. The Phase III randomized double-masked positive-controlled non-inferiority trial is expected