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KPT-330, a selective inhibitor of nuclear export (SINE) chromosome region maintenance protein 1(CRM1) antagonist, is a mediator of nuclear export of p53, p73, pRb, FOXO, p21, p27, BRACA1,

The certification enables Fraunhofer IZI to manufacture as well as supply the DCVax-L product for clinical trials in Germany and throughout the European Union. Fraunhofer said receiving manufacturing

IDX719 is an NS5A inhibitor that demonstrated pan-genotypic activity in a recent proof-of-concept clinical trial in genotypes 1-4, treatment-naive HCV patients. Idenix president and chief executive officer Ron

The single-center trial of aldoxorubicin, a tumor-targeting conjugate of doxorubicin, is designed to enroll up to 24 patients with advanced solid tumors who have failed other therapies. Doxorubicin

The multinational, single-arm, open-label study of JX-594 is administered weekly by intravenous infusions in sorafenib-naive patients with advanced HCC. The trial will be conducted in South Korea, US

The Levetiracetam extended-release tablets, 500mg and 750mg, are the generic equivalent of UCB’s Keppra XR. As per IMS Health, the total combined sales in the US for the

Eltrombopag, known by the brand name Promacta in the US and Revolade in the European Union and other countries, is indicated for thrombocytopenia in patients with chronic immune

The trial will compare Qutenza(R) (8% capsaicin patch) to pregabalin as a treatment for peripheral neuropathic pain. Pregabalin is an oral therapy used to treat peripheral neuropathic pain.

The investment will help the company become premier provider of bio-derived products and critically needed injectables, according to Blackstone. NantWorks and NantPharma chairman Patrick Soon-Shiong said NantPharm will