Immunocore, a T Cell Receptor (TCR) biotechnology company, said that it has dosed the first patient in a phase I study of IMCnyeso, an ImmTAC molecule, as part of a collaboration with GlaxoSmithKline (GSK).
Teva Pharmaceutical Industries and Regeneron Pharmaceuticals reported positive topline results for fasinumab from a phase 3 trial in patients with chronic pain from osteoarthritis (OA) of the knee or hip.
Novocure and US Oncology Research are collaborating on PANOVA-3, a phase 3 pivotal trial testing the efficacy of Tumor Treating Fields combined with nab-paclitaxel and gemcitabine in patients with unresectable locally advanced pancreatic cancer.
Inovio Pharmaceuticals has dosed the first participant with PENNVAX-GP in a randomized clinical trial that will assess its ability to drive remission of HIV infection.
UK-based biopharmaceutical company Izana Bioscience has commenced a phase II proof-of-concept clinical study of namilumab in ankylosing spondylitis.
Samsung Bioepis said that it will soon start a phase 1 study to evaluate its pancreatitis drug SB26 in healthy volunteers.
Spark Therapeutics’ SPK-8011, an investigational gene therapy treatment for hemophilia A, was successful in reducing bleeding in a phase 1/2 trial, but also resulted in one of the participants getting hospitalized.
Summit Therapeutics said that its oral small molecule antibiotic ridinilazole was successful in preserving the gut microbiome of patients with C. difficile infection (CDI) during a phase 2 trial.
Arrowhead Pharmaceuticals has secured a $10m milestone payment from Amgen, following the administration of the first dose of AMG 890, formerly referred to as ARO-LPA, in a clinical study.
Clinical-stage drug development firm Karuna Pharmaceuticals has completed $42m Series A financing round to advance selective muscarinic receptor agonist program into phase 2 study.
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