MEI Pharma and BeiGene have entered into a clinical collaboration to evaluate the safety and efficacy of the combination of their respective drugs ME-401, an investigational PI3K delta inhibitor, and zanubrutinib, an investigational BTK inhibitor, for the treatment of patients with B-cell malignancies.
Bristol-Myers Squibb (BMS) and Compugen have agreed to evaluate the safety and tolerability of the combination of Opdivo (nivolumab) and COM701, their respective drugs, for the treatment of patients with advanced solid tumors.
MaxCyte has dosed the first patient in its US phase I dose-escalation clinical trial of chimeric antigen receptor (CAR) therapeutic candidate, MCY-M11.
The Janssen Pharmaceutical Companies of Johnson & Johnson (J&J) has said that single dose of Stelara (ustekinumab) has induced clinical remission and response in adults with moderate to severe ulcerative colitis (UC).
The National Institute for Health Research (NIHR) said that the first clinical trial of a novel approach to modify the progression of Alzheimer’s disease has commenced at the NIHR University College London Hospitals (UCLH) Clinical Research Facility.
Bial and Eisai said that Zebinix (eslicarbazepine acetate) as monotherapy has been confirmed in the Euro-Esli study to be significantly effective than the same drug as adjunctive therapy for focal-onset epilepsy in adults.
UK-based specialty pharma company Diurnal Group said that its adrenal drug Chronocort failed to meet the primary objective of a phase 3 trial in adults with congenital adrenal hyperplasia (CAH).
hVIVO, is pioneering a human-based clinical trial platform to accelerate drug and vaccine development in respiratory and infectious diseases, has signed two new contracts with global biopharmaceutical company for two respiratory syncytial virus (RSV) human challenge studies.
Merck’s HIV Therapy Delstrigo (doravirine / lamivudine / tenofovir disoproxil fumarate) has achieved primary efficacy endpoint in phase 3 Drive-Shift study, which is assessing switch to Delstrigo from other antiretroviral treatment regimens.
Eli Lilly and Company (Lilly) and Boehringer Ingelheim said that their SGLT2 inhibitor empagliflozin has met the primary efficacy endpoint of a phase III program in adults with type 1 diabetes.
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