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Revealing Kinase Inhibitor Mechanisms: ITC Leads the Way

Published 20 October 2014 | By Malvern Panalytical

The kinome of an organism is the set of protein kinases in its genome and these protein-modifying enzymes are potential targets in a number of therapeutic areas. Studies to characterise the human kinome, together with the explosion of available kinase crystal structures over recent years, have led to an increased focus on kinases as potential targets for pharmaceutical intervention.

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Revealing Kinase Inhibitor Mechanisms: ITC Leads the Way