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Pharmaceutical Business Review
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Pharmaceutical Product Development, Inc. Pharmaceutical Product Development, Inc (PPD) is a global leading contract research organization that provides drug discovery, development and lifecycle management services to its customers. Its drug development services comprise preclinical drug discovery services, programs, Phase I through Phase IV clinical development services and post-approval services, and bioanalytical good manufacturing practices (cGMP), global central laboratory and vaccines and biologics laboratory services. The company provides clinical trial expertise across a wide range of therapeutic areas to over 100 countries, spanning across six continents. In addition, PPD offers support for marketed drugs, biologics and devices, with medical information, patient compliance programs, product safety and pharmacovigilance, patient and disease registry programs, observational studies, standard response document development, Phase IV monitored studies and prescription to over-the-counter programs. The company operates under two business segments, Clinical Development Services and Laboratory Services. It owns and operates 86 offices across 43 countries worldwide. The company’s partners and clients include biotechnology, pharmaceutical, medical device, academic, government and non-profit organizations. PPD is headquartered in Wilmington, North Carolina, the US. Company Data Blue Cross Blue Shield of Michigan Blue Cross Blue Shield of Michigan (BCBSM) is an independent non-profit organization providing and administering health benefits to the residents of Michigan, and the members of Michigan-headquartered groups residing outside the state. The organization delivers health insurance services in the Michigan state under license from the Blue Cross Blue Shield association. BCBSM offers health care coverage, including individual coverage, group coverage, Medicare plans, managed plans, health management plans, medical and dental care programs. The company also offers prescription drug coverage, preventive care and office visits plans, medical plan with a health savings account, and healthy communities grant programs. The company along with its subsidiaries primarily operates in the Michigan state of the US. BCBSM is headquartered in Michigan, the US. The company seeks to enhance its patient-centered medical home program through strategic collaborations with doctors and hospitals. Company Data Lombard Medical Technologies PLC Lombard Medical Technologies PLC (LMT) is a medical technology company. The company focuses on the development, manufacture, and supply of endovascular stent-grafts that address unmet needs in the repair of aortic aneurysms. It specializes in the development of device solutions for the abdominal aortic aneurysm (AAA) repair market. The flagship product of the company, Aorfix, is the only AAA, approved by the FDA to treat aneurysms in complex anatomies with neck angulations of up to 90 degrees. LMT markets Aorfix in the UK through its sales force and is sold in Europe and parts of South America through a network of local distributors. It has operations in the US and the UK. LMT is headquartered in Didcot, Oxfordshire, the UK. Company Data Hologic, Inc. Hologic, Inc. (Hologic) is a leading developer, manufacturer and supplier of premium diagnostic and medical imaging systems exclusively serving the healthcare needs of women. The company is also a leading developer of imaging technology for digital radiography and breast imaging applications. Hologic's core business units are concentrated on mammography and breast biopsy, osteoporosis assessment, surgical devices for gynecology, mini C-arm and extremity MRI imaging for orthopedic procedures. The company operates in North America, Europe, Central America, Australia and Asia. Hologic is headquartered in Bedford, the US. The company focuses on thoughtfully designed innovations, based on extensive consumer insight, to meet the needs of hospitals and physicians. Hologic envisages establishing its position through the development of innovative products and services and enhancement of existing ones, internal development, strong partner relationships, strategic collaborations and acquisitions. Company Data Bristol-Myers Squibb Company Bristol-Myers Squibb Company (BMS) is global biopharmaceutical company focused at addressing the unmet medical needs of patients with serious diseases. It undertakes the discovery, development, licensing, manufacture, marketing and distribution of biopharmaceuticals and related healthcare products. The company focuses on the areas including cancer, psychiatric disorders, cardiovascular disorders, diabetes, hepatitis B, HIV/AIDS and rheumatoid arthritis. Its product line includes chemically-synthesized drugs and biological products. BMS has research and development facilities in the US, Belgium, England, France and Japan; and it also has manufacturing facilities in Puerto Rico, the US, France, Italy, Ireland, Japan, Mexico and China. BMS is headquartered in New York, the US. The company focuses on thoughtfully designed innovations, based on extensive consumer insight, to meet the needs of hospitals and clinics. BMS envisages establishing its position through the development of innovative drugs and enhancement of existing ones, internal development, strong partner relationships, strategic collaborations and acquisitions. Company Data F. Hoffmann-La Roche Ltd. F. Hoffmann-La Roche Ltd. (Roche) is a research-focused healthcare company. It discovers, develops, manufactures and markets innovative diagnostics and therapeutic products and services. Roche's products and services address the prevention, diagnosis and treatment of diseases, and improve the well-being and quality of life of patients. The company specializes in in-vitro diagnostics and drugs for cancer and transplantation. Roche classified its operations into two reportable business segments, namely, Pharmaceuticals and Diagnostics. Geographically, the company has operations in various countries across North America, Latin America, Europe Asia, Africa, Australia and Oceania. Roche is headquartered in Basel, Switzerland. Roche envisages establishing itself in the market through new product launches, network expansion, internal development, in-licensing of technology and products, acquisitions and strategic alliances. Company Data Teva Pharmaceutical Industries Limited Teva Pharmaceutical Industries Limited (Teva) is a fully integrated global pharmaceutical company. It undertakes the development, manufacture and marketing of a wide range of generic and branded pharmaceuticals and active pharmaceutical ingredients (APIs). The company offers chemical and therapeutic equivalents of originator pharmaceuticals in a wide range of dosage forms, including capsules, tablets, ointments, liquids, creams, injectables and inhalants. Teva also provides an array of over the counter (OTC) products through a joint venture with P&G. The company is also a specialty pharmaceuticals innovator focusing on various disease areas including multiple sclerosis, Parkinson's disease, autoimmune diseases, cancer, women's health and respiratory products. Teva operates in more than 60 countries and distributes its products across the world. Teva is headquartered in Tikva, Israel. Teva seeks to maintain and expand its leadership position in the global generics market. The company adopts organic and inorganic growth strategies to achieve its goal. Company Data Varian Medical Systems, Inc. Varian Medical Systems, Inc. (Varian) is a provider of medical devices and software for the treatment of cancer. It designs, manufactures and sells equipment and software for the diagnosis and treatment of cancer and other medical conditions through radiotherapy, radiosurgery, proton therapy and brachytherapy. The company offers X-ray tubes and digital image detectors that are used in medical, dental, veterinary, scientific and industrial sectors. It designs, manufactures, sells and services linear accelerators, image processing software and image detection products for security and inspection purposes and proton therapy products and systems for cancer treatment. The company, together with its subsidiaries and manufacturing facilities, operates in North America, Europe, Asia-Pacific, the Middle East and Africa. Varian is headquartered in Palo Alto, California, the US. Company Data Zimmer Holdings, Inc. Zimmer Holdings, Inc. (Zimmer) is a medical device company. It carries out the design, development, manufacture, and marketing of reconstructive orthopaedic implants, dental implants, spinal and trauma products and related orthopaedic surgical products. Its major product line comprises orthopaedic reconstructive product line that includes knee implants, hips implants and extremities; dental implants; trauma products; spine implants; and orthopaedic surgical products. Zimmer has direct presence in around 25 countries the world over and sells its products in over 100 countries. Its major markets are concentrated in Americas, Europe and Asia Pacific. Zimmer is headquartered in Indiana, the US. Zimmer seeks to elongate its leadership position in musculoskeletal health market through focusing on joint reconstructive category and other musculoskeletal categories like, extremities and emerging businesses. Besides, it carries out massive geographical expansion initiatives to tap high value multinational clients. Company Data AtriCure, Inc. AtriCure, Inc. (AtriCure) is a medical device company. It carries out the development, manufacture and sales of innovative cardiac surgical ablation devices. The company's ablation devices are designed to create precise lesions or scars in cardiac and soft tissues. The major products of the company include AtriCure Synergy Ablation System, a bipolar ablation clamp system and related radiofrequency ablation devices; Estech’s radio frequency ablation devices; AtriClip left atrial appendage (LAA) occlusion system; and a cryoablation product line that features reusable and disposable cryoablation devices. The company markets and sells its products in selected markets outside of the US through independent distributors and through its European subsidiary in EMEA markets. AtriCure is headquartered in Ohio, the US. The company focuses on the expansion of its product portfolio by building a strong operating base, besides gaining expertise through acquisitions and collaborations. AtriCure seeks to obtain expanded US FDA clearances and approvals in order to achieve market acceptance for its products. Company Data Fresenius SE & Co. KGaA Fresenius SE & Co. KGaA (Fresenius) is a global health care group, which offers products and services for dialysis treatment. It provides various dialysis services through its own clinics and sells its products to other dialysis service providers. Its major products and services includes machines for hemodialysis, acute dialysis and peritoneal dialysis; solutions for infusion therapy; dialysis care services; Spectra laboratories; liver support therapy services; and provision projects and services for hospitals and other health care facilities. It also operates and manages acute care and postacute care hospitals in Germany through HELIOS Kliniken Group. Fresenius conducts operations in Asia-Pacific, Europe, Africa and the Americas. Its major manufacturing plants are in the US, Germany, China, Sweden and Japan. The company is headquartered in Bad Homburg, Germany. Company Data Nektar Therapeutics Nektar Therapeutics (Nektar) is a biopharmaceutical company. It carries out discovery and development of a pipeline of novel therapeutic drug candidates based on its PEGylation and advanced polymer conjugate technology platforms to address unmet medical needs. The product pipeline of the company focuses on various therapeutic areas, including, oncology, pain, anti-infectives, anti-viral and immunology among others. The company’s technology has enabled seven approved products in the US and Europe through partnerships with leading biopharmaceutical companies, including Roche's PEGASYS for hepatitis C, Amgen's Neulasta for neutropenia and UCB's Cimzia for Crohn's disease and rheumatoid arthritis. Its research and development activities involve peptides, small molecule drugs, and other potential biologic drug candidates. Nektar Therapeutics is headquartered in San Francisco, California, the US. Company Data Isis Pharmaceuticals, Inc. Isis Pharmaceuticals, Inc. (Isis) is a bio-pharmaceutical company. The company specializes in anti-sense technology. It carries out the discovery and development of new class antisense drugs that address significant unmet medical needs. Antisense technology is a direct route from genomics to drugs. KYNAMRO (mipomersen sodium) injection is the lead product candidate of the company which has been developed in collaboration with Genzyme. It is used for the reduction of low-density lipoprotein cholesterol in patients suffering from homozygous familial hypercholesterolemia, or HoFH. The product pipeline of the company focuses on various therapeutic areas, namely, cardiovascular, cancer, metabolic, neurodegenerative, inflammatory and other diseases. The products in the pipeline include ISIS-CRP, ISIS-FXI and ISIS-APO(a). Isis is headquartered in Carlsbad, California, the US. Company Data Eli Lilly and Company Eli Lilly and Company (Lilly) is a US based innovation driven pharmaceutical company. It carries out the discovery, development, manufacture and marketing of products. The company’s product portfolio consists of neuroscience products, endocrinology products, oncology products, cardiovascular products, animal health products and other pharmaceutical products. The company’s research efforts are mainly focused on five therapeutic domains, namely, cancer; endocrine diseases such as diabetes, obesity, and musculoskeletal disorders; central nervous system; autoimmune diseases; and cardiovascular diseases. The company’s product are sold in several countries across the world. Lilly is headquartered in Indiana, the US. The company focuses on creating value for all its stakeholders by enhancing the flow of innovative new medicines that provide improved outcomes for individual patients. Company Data Vertex Pharmaceuticals Incorporated Vertex Pharmaceuticals Incorporated (Vertex) is a biotechnology company. It carries out the discovery, development and commercialization of small molecule drugs for the treatment of serious and life-threatening ailments. The company offers Incivek (telaprevir), approved for the treatment of patients with genotype 1 hepatitis C virus (HCV) infection, and Kalydeco (ivacaftor), approved for the treatment of patients with cystic fibrosis (CF). The company’s research and development efforts focus on influenza and bacterial infections, inflammatory diseases, cancer, neurological diseases and disorders including pain, and cystic fibrosis. The company has a major presence in the US, the UK, and Canada. Vertex is headquartered in Boston, Massachusetts, the US. The company’s strategic business objectives include global Launch of Kalydeco in cystic fibrosis and expansion of its Kalydeco development program. Company Data Merck & Co., Inc. Merck & Co., Inc. (Merck), also known as MSD outside the US and Canada, is a research-driven global healthcare company. It conducts the discovery, development, manufacture and commercialization of branded pharmaceuticals, biologic therapies, prescription and over-the-counter (OTC) pharmaceuticals, vaccines, consumer care products and animal healthcare products. The company has four operating units, namely, Pharmaceuticals (primary segment), Animal Health, Consumer Care and Alliances. The major clients of the company include wholesalers and retailers, hospitals, government agencies, managed health care providers, and veterinarians. Merck sells its products through direct sales force and a network of subsidiaries and joint ventures across the US, Europe, the Middle East and Africa, Asia Pacific and Other countries. Merck is headquartered in Whitehouse Station, New Jersey, the US. Company Data Stryker Corporation Stryker Corporation (Stryker) is one of the leading manufacturers of medical equipment. It offers reconstructive, medical and surgical, and neurotechnology and spine products. Its major products include implants; surgical equipment and surgical navigation systems; endoscopic and communications systems; patient handling and emergency medical equipment; neurosurgical, neurovascular and spinal devices; and medical devices used in a variety of medical specialties. Stryker sells its products in the US, Europe, Japan, Asia Pacific, Canada and Latin America. It sells its products through its subsidiaries and branches, besides third-party dealers and distributors. Stryker is headquartered in Michigan, the US. The company's strategy is to gain a strong foothold in the healthcare arena and expand its operations in a highly innovative, high-growth space, which would enable it to become a market leader in the neurovascular area. In line with this strategy, the company acquired Pivot Medical, Inc., Patient Safety Technologies, Inc., and MAKO Surgical Corp. in early 2014. Company Data Royal DSM N.V. Royal DSM N.V. (DSM) is a global life sciences and materials sciences company. It primarily focuses health, nutrition and materials sectors. The company offers a wide range of products, ranging from anti-invectives, polyesters, vitamins, to oil and gas across diverse end markets. It offers its products and services to animal and human health and nutrition, personal care, pharmaceuticals, automotive, medical materials, food and beverages, packaging, electrical and electronics, coatings and paint, alternative energy, housing, and life protection markets. DSM is headquartered at Heerlen, Netherlands. The company’s strategy has been to expand its activities across major regions through acquisitions and joint ventures. In line to its business, the company acquired 19% interest in Yantai Andre Pectin Co. Ltd., a China-based producer of texturing ingredients. Company Data GlaxoSmithKline plc GlaxoSmithKline plc (GSK) is one of the world’s leading research-based pharmaceutical and healthcare companies. It focuses on the development, manufacture and commercialization of pharmaceutical and consumer health related products. The company offers medicines for the treatment of various diseases such as infections, asthma, diabetes, cardiovascular, mental health and digestive conditions. GSK's research and development activities focus on the development of medicines and vaccines for HIV/AIDS, tuberculosis and malaria. The company also offers antiviral drugs, vaccines, consumer healthcare products and medicines for asthma, cardiovascular and digestive conditions, diabetes, infections and mental health. It operates research facilities in the UK, the US, Belgium, Spain, and China. GSK is headquartered in Middlesex, the UK. GSK aims at offering high quality medicines and vaccines to enhance the quality of human life around the world. Its strategy is to improve long-term financial performance with a diversified business model, enhance R&D returns, and deliver a diverse line of products, while simplifying its operating model. The company also aims at maintaining its existing partnerships and entering into new collaborative agreements to augment its services. Company Data AstraZeneca PLC AstraZeneca PLC (AstraZeneca) is a biopharmaceutical company that carries out designing, developing, production and marketing of various range of biologics, prescription pharmaceuticals and vaccines for the treatment of diseases such as cancer, cardiovascular, gastrointestinal, infection, neuroscience, respiratory and inflammation. It offers a wide portfolio of products in various therapeutic areas, some of which include Crestor, Seroquel, Arimidex, Nexium and Symbicort. Its research and development activities focus on the development of pharmaceutical products for certain indications such as type 2 diabetes, infection, COPD, cancer, Alzheimer's disease and others. Geographically, the company has its presence in more than 100 countries the world over. It has research and development sites in six countries and manufacturing plants in 17 countries. AstraZeneca is headquartered in London, the UK. Company Data
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