Target Validation

How can you speed up the development of new pharmaceutical compounds, at reduced costs? What fertility and reproduction assays are available for high throughput drug screening? EggCentris offers rapid answers to this essential intermediate step between screening and in vivo testing.

EggCentris provides in vitro tests that assess the activity directly at the biological target of the drug compound. Our relatively high speed and straightforward tests allow you to screen large numbers of compounds in a short time. With this quicker and more selective screening, you end up with fewer but better potential candidates for in vivo testing and further development.

Broadly applicable, multiparametric fertility tests

EggCentris has developed a number of in vitro bioassays that enable the in vitro exposure of all possible target systems in the female reproductive system:

• Follicle bioassay (FBA): multiparametric test for simultaneous evaluation of folliculogenesis, steroidogenesis, and oogenesis as it mimics in vitro the physiological processes of the ovary
• In vitro maturation assay (IVM): multi parametric assay to evaluate the meiotic process of the oocyte
• In vitro fertilisation assay (IVF): verifies how the compound can disturb the process of conception
• Mouse embryo assay (MEA): analyses pre-implantation embryo development

We also develop new testing models on your request, fully adapted to your specific needs and the compounds under study.