Synthesis Programme

At Trigona we are able to run a complete synthesis programme for you which covers route scouting, sourcing of starting materials, synthesis, processing, analysis, documentation and shipment.

We carry out contract research for example to develop a process, to explore synthesis pathways and to generate biologically active test compounds. Trigona prepares:

• Analytical standards
• Cold isotopomers
• Final catalogue compounds
• Final products
• Intermediates
• Metabolites
• Research compounds
• Screening compounds

Capabilities

What we do:

• General organic chemistry
• mg’s to multi-kg’s
• Temperature range from -100°C to +200°C
• Reactions under inert conditions
• Metalorganic reactions
• Reactions with phosgene, borontrichloride…

What we can’t handle:

• Reactions under pressure
• Explosive materials
• Radioactive materials

Equipment

• Standard lab equipment and glassware up to 10L
• 10L, 20L, 30L glass reactors
• 40 and 63l multipurpose glasslined steel reactors
• 300L glas- and steel vessels
• 20l rotary evaporator
• Vacuum and inertgas equipment
• Low temperature equipment
• Parallel synthesis reaction block

Trigona has a number of options to perform qualitative and quantitative analysis for raw material check, in-process control and product performance.

• NMR-spectrometer
• HPLC, GC/MS, DSC
• Karl-Fischer apparatus
• Melting point apparatus
• Wet chemical analysis