Scaling-up & Pharmaceutical Assessment Programs

Following any screening programs SARA PHARM offers the possibility of scaling-up (to 30-50g) processes of the most important crystalline phases and stable ASD systems, followed by full characterization including Differential Scanning Calorimetry (DSC), TGA, XRPD and Single Crystal analysis (applicable to crystalline forms), Dynamic Vapor Sorption (DVS or GVS), thermodynamic and kinetic solubility and a range of other analytical tests (e.g pKa, logP/logD, NMR, IR, Raman) which are key items in pharmaceutical development.