Pharmacokinetic Studies

Our large database of more than 1000 healthy volunteers provides subjects for a variety of pharmacokinetic studies.

Shandon also has access to elderly volunteers through a strategic partnership, purposefully developed to allow access to further test resources.

Shandon Clinic offers the following types of pharmacokinetic studies:

• Relative bioavailability of established and experimental formulations
• Single and multiple dose kinetic studies
• Food-effect kinetic studies
• Selected interaction studies
• Pharmacokinetic analyses of pilot and development batches of medicines
• Immediate and modified release formulations
• Kinetics in slow and fast metabolisers (genotyped, phenotyped)
• OTC and prescription-only drugs

We have experience of a variety of delivery systems including tablets, capsules, solutions and suspensions, transdermal, intranasal, buccal and rectal applications, as well as products designed for topical application to various parts of the body.

Shandon has specific expertise in the conduct of pilot studies with formulations designed for delayed release and commonly performs studies looking at food interaction.

Past studies have covered most therapeutic areas, including:

• Anti-infectives
• Neuropsychiatric agents
• Non-steroidal anti-inflammatories
• Anti-hypertensives
• Anti-diabetic agents
• Drugs used in peptic ulcer disease
• Anti-tussives
• Anti-histamines
• Corticosteroids
• Diuretics