The greatest reason for drug candidates failing during clinical development remains a lack of desired clinical effect. In addition many promising test compounds still fall out of development due to unforeseen side effects or unfavorable pharmacokinetic profiles1,2.
|Asterand performs a variety of human cell-based assays to generate data that support the identification and selection of compounds with the best characteristics for further pre-clinical and clinical development. Studies can be designed to determine the potency, effect, disposition and safety of test compounds in human tissues. Data generated in human tissue-based models allows pre-clinical go/no-go decisions for drug candidates and formulations to be taken with more confidence for getting the right compounds into the clinic.|
The services we provide apply across a range of different therapeutic research areas. Click here to download a summary of which PhaseZERO® services can be accessed within your therapeutic area of interest.
We aim to facilitate the identification and selection of drug candidates with an increased likelihood of clinical success. Our human tissue-based approach allows rapid and early evaluation of compounds in biologically relevant tissues to:
For over ten years our scientists have been consulted by and have collaborated with top, global pharmaceutical companies. We help our customers evaluate candidate compounds, providing a consultative, tailored scientific approach in order to deliver high quality human tissue-based data on the potency, efficacy, disposition and safety of test compounds.
We provide a wide range of standard and custom assays in the following areas:
Working with Asterand