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Bioprocess and Formulation Development

Rentschler

Rentschler delivers upstream process (USP) development for cell cultivation and downstream process (DSP) development for protein purification as well as formulation development.

  • Process development
    – Platform & customized
    – High cell density & high titer
    – Batch, fed-batch, continuous & perfusion
    – Non-GMP production up to 250 L
  • Scale-up and process transfer to production scale
  • Process characterization, scale-down modelling and validation
  • Transfer and optimization of client’s bioprocesses
  • Liquid formulation development
  • Preliminary protein characterization including stress-degradation
  • Evaluation of indicative analytical methods
  • Parameter screening (pH, buffers, ionic strenghts, excipients, surfactants)

bioprocess & formulation development

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