News

Recessive mutations in a gene called phospholipase C epsilon, or PLCE1, have been identified as the cause of a kidney disease called nephrotic syndrome. Untreated nephrotic syndrome progresses

CRx-102 is an oral synergistic combination drug candidate containing the cardiovascular agent dipyridamole and a low dose of the steroid prednisolone. The trial compared CRx-102 plus a disease-modifying

In North America, this fifth recommendation by the monitoring board was based on the recent review of the available safety data from 1,052 patients who have been on

Ablynx is the pioneer in the discovery and development of nanobodies, a novel class of antibody-derived therapeutic proteins. The agreement will allow the companies to develop and commercialize

Mesd is a chaperone protein necessary for the proper folding of the signal transduction receptors LRP5 and LRP6. Mesd-based peptides may be useful in the therapeutic regulation of

The drug, which is manufactured by Japan’s Eisai and co-promoted in many markets by Pfizer, will be given daily for six months to brain cancer survivors who have

The phase IIb clinical study will be designed primarily to evaluate the efficacy, safety and tolerability of the Tovaxin T Cell vaccination with clinically isolated syndrome and relapsing-remitting

The assessment of AMG 706 in 120 patients showed a clinical benefit rate of 27%. Treatment-related adverse events that occurred in 15% or more of all patients were

The results suggest that PTC124 can restore function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein in airway cells and significantly reduce blood neutrophil counts that are