Clinical Trials

Myovant’s hormonal therapy relugolix succeeds in phase 2 trial

Myovant Sciences has reported positive results from a placebo-controlled Phase 2 dose-finding trial evaluating the ability of relugolix to decrease heavy menstrual bleeding in women with uterine fibroids which was conducted by Takeda Pharmaceutical in Japan.

Relvar Ellipta improves asthma control in Salford Lung Study

GlaxoSmithKline and Innoviva said that their asthma drug Relvar Ellipta yielded positive results from the Salford Lung Study (SLS) in 4,233 asthma patients treated by their own general practitioner in everyday clinical practice.

Laquinimod fails to meet primary endpoint in multiple sclerosis trial

Teva Pharmaceutical Industries and Active Biotech announced that CONCERTO trial for laquinimod in patients with relapsing-remitting multiple sclerosis (RRMS) failed to meet its primary endpoint.

Clinical trial technology firm Science 37 raises $29m funding

Science 37 has raised $29m in Series C funding, led by Glynn Capital Management with participation from GV, to bring clinical trials directly into patients’ homes.

Pfizer’s Zavicefta matches standard-of-care in treating hospital-acquired pneumonia in phase 3 study

Results from the phase 3 REPROVE study assessing Pfizer's fixed-dose antibacterial combo Zavicefta (ceftazidime-avibactam) in patients with hospital-acquired pneumonia (HAP) demonstrated a comparable cure rate to carbapenem antibiotic therapy, considered the standard of care.

NGM Bio’s NGM282 succeeds in nonalcoholic steatohepatitis phase 2 trial

NGM Bio’s NGM282 has met the primary and key secondary endpoints in a Phase 2 trial in nonalcoholic steatohepatitis (NASH) patients.

Ultragenyx’s hypophosphatemia drug succeeds in phase 3 study

Ultragenyx Pharmaceutical, Kyowa Hakko Kirin and Kyowa Kirin International have reported positive 24-week data from the randomized, double-blind, placebo-controlled Phase 3 trial of burosumab (KRN23) in X-linked hypophosphatemia (XLH) adult patients.

Relypsa’s Veltassa shows consistent efficacy in phase 4 trial to treat hyperkalemia

Relypsa’s Veltassa (patiromer) has demonstrated consistent effficacy and safety in phase 4 Tourmaline study in patients with hyperkalemia.

Mateon’s phase 2/3 trial in platinum-resistant ovarian cancer yields positive results

Mateon Therapeutics has revealed encouraging data from its first interim scheduled analysis of the ongoing phase 2/3 trial (FOCUS) in platinum resistant ovarian cancer (prOC) patients.