Trehalose is a naturally occuring non-reducing disaccharide consisting of two glucose molecules. 

It plays an important role in cryoprotectant in the production of protenious drugs and it also prevents proteins in plant cells and other molecules from damaging on freezing.

Understanding the stability conditions and properties of the different phases is essential for the optimisation of production processes and storage conditions for drugs.

In the past, x-ray diffraction (XRD) in the vicinity of the stability limits of trehalose were difficult due to dew point limits of commercially available set-ups.