Accurately measuring the particle size distribution of a sample relies on various factors. Foremost amongst these is a reliable, high-precision sizing instrument. Equally as important is the successful dispersion of the sample to its constituent primary particles.
Efficient dispersion of a sample relies on the careful selection of the dispersing medium and a range of surfactants and additives. In addition, the application of ultrasound to physically separate particles can ensure a good dispersion.
Achieving the correct dispersion conditions for your particular sample is a fine balance. The instrument will report a particle size distribution, which is inclusive of any agglomerations of particles in the sample, and often leads to a skewed reported particle size.