Pharmaceutical Business review

Novimmune signs international research collaboration deal with Baxalta

Financial terms of the deal were not disclosed.

This is the first collaboration utilizing Novimmune’s new kappa-lambda bispecific antibody technology. The proprietary platform generates fully human antibodies which target two specific binding sites with one antibody.

Novimmune CEO Jack Barbut said: "The kappa-lambda platform is exactly the right technology for therapy areas which need a bispecific antibody that is as close to a natural human antibody as you can get.

Bispecific antibodies currently used in biopharmaceutical applications have been constructed using chemical linkers, non-human material, antibody fragments or forced engineering, he said.

Head of Research Nicolas Fischer said: "Our kappa-lambda antibodies are allowed to assemble naturally.

"So, they have promising development and safety characteristics such as a longer half-life, increased stability and a lower risk of provoking an unwanted reaction in patients."