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Carinthian Tech Research (CTR)

Providing Intelligent Sensor Solutions to Life Science Manufacturers

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LATEST PRESS RELEASES
September 20, 2010

Multispectral Data Helps Diagnose Cancer

In endoscopy, there have been attempts for many years to show doctors important additional information live on the endoscopy video...
pharmacuetical business review
September 19, 2010

Malignant Cells? Spectral Image Processing and Improved Image Contrast Facilitating Diagnosis

By Birgit Rader-Brunner. Scientific cancer research is based on the microscopic monitoring of cells and tissue. Now, methods of spectral...
pharmacuetical business review


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Carinthian Tech Research (CTR)

Carinthian Tech Research (CTR) is a reliable partner for industry-oriented research and development in the area of intelligent sensor systems and one of Austrians leading research competence centres.

CTR provides a full range of R&D services and development for the life sciences, medical, automation, and manufacturing industries.

Intelligent sensor solutions

The R&D center helps companies to optimise existing procedures and develop new intelligent sensor solutions in the field of automated process and quality control. CTR is a link between science and industry using the latest findings to make products and production processes simpler, faster, safer and more effective.

Core competences:

  • Optical sensor systems
  • SAW sensor systems
  • Photonic microsystems

Optical sensors, sensor prototypes and software development

Optical sensors (UV–VIS–NIR–MIR), spectral imaging, imaging spectroscopy, machine vison and image processing, x-ray, raman imaging, terahertz (THz) imaging spectroscopy, fluorescence spectroscopy, chemometry, statistical classification, sensor prototypes and software development, algorithms, expertise in handling and automation technologies, optical simulation and design, microsystems, micro-optical systems (MEMS/MOEMS), wireless sensing and identification tasks.

R&D services

CTR delivers in-depth expertise at every stage of implementation – from feasibility studies, conception and design through prototyping, simulation and testing to finished system and product solutions. The team at CTR includes electrical engineers, mechanical engineers, mathematicians, chemists, physicists, computer scientists, telemetry and mechatronics experts. The R&D expertise is aimed at customer-oriented requirements and focuses on project-benefit and exploitation.

Medical / pharmaceutical applications

  • Evaluation of skin lesions with spectral imaging
  • Fully automated chemical process interpretation
  • Multimode-detection platform with integrated image processing
  • Analysis of unmixed hyper-spectral M-FISH images for supporting breast cancer treatment decision
  • Automated inspection system of stents
  • MEMS-based high-speed FT-IR spectrometer – a new platform for real-time IR-spectroscopy and process control
  • Multi-analyse in-situ process control of industrial biopharmaceutical microorganism fermentations
  • Light induced time-resolved flow-flash FTIR investigation in micro-mixing cells

Business partners: Beckman Coulter, Bruker, Boehringer Ingelheim, Ortner Reinraumtechnik, Unisensor, Siemens, Wild Austria, Wolf, Roche Diagnostics.

Scientific partners: Fraunhofer Institut für Mikroelektronische Schaltungen und Systeme (D), Technische Universität Clausthal (D), Danish Technology Institute (DK), Technische Universität Wien (A).

 

CTR Carinthian Tech Research AG
Europastraße 4/1
9524 Villach
AUSTRIA

Tel: 43(0)4242 56300-0
Fax: 43(0)4242 56300-400
info@ctr.at
www.ctr.at

In-Situ Multi-Analyte Sensing in Industrial Biopharmaceutical Microorganism Fermentations

Mid-IR ATR sensors are a highly interesting tool for in-situ real-time process monitoring of industrial micro-organism fermentations.

An increasing number of modern, highly effective pharmaceuticals are produced in advanced biotechnological fermentation processes. For optimised process control, a good understanding of the processes involved and fast monitoring of analyte concentrations are valuable assets. Hence, in-situ chemical sensors replacing the prevalently used at-line I offline analytics are of high interest. This is all the…

Light Induced Time Resolved Flow-Flash FTIR Investigation in Micro Mixing Cells

The project could demonstrate the coupling of a flow-flash experiment with IR step-scan measurements for the first time. This widens the applicability of the step-scan technique to monitor slow cyclic reactions such as the reaction of the retinal protein with light or even to the reaction of cytochrome c oxidanse with oxygen.

The method is particularly interesting for samples which are only available in small quantities, such as biological samples, due to its small sample consumption. Abstract In this work we present our latest developments for step scan FTIR measurements to widen its applicability to noncyclic reactions. With our approach the reaction between two chemicals can be…

MOEMS Spectrometers: Making Spectroscopic Chemical Sensors Fast and Mobile

Small compact micro-electro-mechanical systems (MEMS) can build pocketsized spectrometers for various spectral ranges, including the near-IR or mid-IR.

One main obstacle in using infrared spectroscopic chemical sensors in out-of-the-lab applications is the lack of suitable spectrometers. Presently, most spectrometers for infrared wavelengths are comparatively large, stationary and expensive. Additionally, the use of massive optical components, like gratings or mirrors, severely limits the time resolution of such systems. With the advent of small, compact…

Spectral Unmixing for Hyperspectral Images of Breast Cancer Preparations

The scientific cancer research is based on the microscopic monitoring of cells and tissue. Now, methods of spectral image processing improve the image contrast and support medical diagnostics via software solutions.

Breast carcinoma is the second most common form of cancer among women [1]. Multicolour fluorescent in-situ hybridisation (M-FISH) is a common method for staging breast carcinoma. The interpretation of M-FISH images is complicated by two effects: (i) the emission spectra of the fluorochrome marked DNA probes overlap each other, and (ii) healthy tissues auto fluorescence.…
Quick Contact Carinthian Tech Research (CTR)
Quick Contact Carinthian Tech Research (CTR)


Quick Contact Carinthian Tech Research (CTR)
Quick Contact Carinthian Tech Research (CTR)
Quick Contact Carinthian Tech Research (CTR)


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