MHC is a large cluster of genes found on the short arm of chromosome 6 including 150 expressing genes which progresses diseases like AIDs, arteriosclerosis, cancers, diabetes and leukemia.
The new technology is based on NimbleGen’s revolutionary process for the enrichment of the MHC region – SeqCap EZ Choice Library.
MHC region capture technology targets the traditional MHC region (3.37MB) and also approximately 1.6Mb of the regions surrounding MHC, providing a total of 4.97Mb (chr6: 28477797-33448354) and includes 8 known haplotypes.