Pharmaceutical Business review

BioCryst terminates merger deal with Idera Pharmaceuticals

Image: BioCryst scraps merger deal with Idera Pharmaceuticals. Photo: courtesy of jk1991 / FreeDigitalPhotos.net.

Idera said that majority of its stockholders voted in favor of the adoption of the merger agreement with BioCryst.

BioCryst will pay $6m as transaction-related expenses to Idera, as per terms of the merger agreement.

BioCryst Pharmaceuticals president and CEO Jon Stonehouse said: “We respect and understand the views of our stockholders and are moving forward fully-focused on executing our business plan as a standalone company.

“The BioCryst Board and management team remain confident in BCX-7353 and our ability to execute on our plan and advance our programs.”

In January this year, BioCryst signed a merger agreement with Idera to create a new entity focused on the development and commercialization of medicines for the treatment of patients with rare diseases.

Under the deal, BioCryst agreed to own 51.6% of the stock of the combined firm, while Idera agreed to own the remaining 48.4% in the combined company.

BioCryst is engaged in the design and development of novel small-molecule medicines for both common and rare conditions.

The firm has various ongoing development programs, including a preclinical program to develop oral Alk-2 inhibitors for the treatment of fibrodysplasia ossificans progressiva (FOP).

Its development programs also include BCX735, an oral treatment for hereditary angioedema, and galidesivir, a potential treatment for filoviruses.

BioCryst’s first approved product is Rapivab (peramivir injection), which a viral neuraminidase inhibitor for the treatment of influenza.

The firm secured regulatory approval for Rapivab in the US, Canada, Japan, Taiwan, Australia, and Korea.

Idera is a clinical-stage patient-focused biopharmaceutical firm engaged in the development of novel nucleic acid therapeutic approaches to treat certain cancers and rare diseases.

The firm has designed third-generation antisense technology to inhibit the production of disease-associated proteins by targeting RNA.

Idera CEO Vincent Milano said: “The Board and shareholders of Idera overwhelmingly supported the proposed merger with BioCryst based on the strategic rationale, operating synergies and opportunity to create a stronger and more diversified rare-disease, focused organization.”