Pharmaceutical Business review

American CryoStem announces breakthroughs in expansion and lineage-specific differentiations of ADSCs

Breakthroughs in American CryoStem’s proprietary cell culture medium (ACSelerate) and culturing methodology have enabled the Company to accelerate the robust cellular expansion and rapid differentiation of ADSCs to adipocytes (fat cells), chondrocytes (cartilage-producing cells) and osteocytes (bone-producing cells).

Working with its patented media technologies, the company has been able to accelerate early adipocyte formation to within 24 to 72 hours; to produce chondrocyte filaments contracting into early cartilaginous tissue within 48 to 72 hours; and to form heavily mineralized, trabecular bone tissue within 11 days — processes that typically require several weeks to complete.

American CryoStem chief scientist Dr Michael Moeller noted that the development of rapid, efficient and reproducible methods of differentiating distinct mature cells from adipose tissue will prove invaluable to the Regenerative Medicine industry.

"The ability to quickly grow large numbers of ADSCs from patient samples and to rapidly differentiate them into distinct lineages will open the door to multiple therapeutic and regenerative approaches supported in our ongoing university and corporate collaborations," Dr Moeller added.