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Going with the Flow: Malvern Instruments' Basic Introduction to Rheology
| By Malvern Instruments
Rheology concerns itself with materials that have aspects of both solids and liquids, and researches the flow and deformation of matter. Malvern Instruments explores this study, and reveals its fundamental in relation to force, deformation and time.
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Malvern Instruments Shares its Buyer's Guide to Protein Stability Measurement Platforms
| By Malvern Instruments
As a leader in best practices during biopharmaceutical development, Malvern Instruments sheds light on effective protein stability analysis technologies for the biopharmaceutical industry.
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Reliable, Long-range Wireless Sensors for Environmental Monitoring
| By Vaisala pbr
The Vaisala viewLinc Monitoring System tracks environmental conditions wirelessly using Vaisala’s VaiNet wireless devices based on LoRa™* technology. By using a chirp spread spectrum (CSS)* wireless protocol, VaiNet provides robust communication that is extremely reliable over long distances and under harsh, complex and obstructed conditions.
Contract Research & Services > Clinical Trials > White Papers
Five Ways That the Mastersizer 3000 Saves you Money
| By Malvern Instruments
To earn its place in today’s busy analytical laboratories, an instrument must meet certain practical criteria, and stand-up to rigorous economic evaluation. For labs that need particle sizing, laser diffraction systems are typically the technology of choice; delivering accurate and reliable information for the broadest range of sample types. Here, we look at how the Mastersizer 3000, the market leading laboratory particle size analyzer from Malvern Instruments, can save you time, money and resources, and ultimately deliver a healthy return on investment.
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Time to Spec up? Top Five Reasons to Replace a Viscometer with a Rheomete
| By Malvern Instruments
Is your viscometer approaching the end of its life? Are you starting to feel that your trial and error, ‘rheology-light’ approach to formulation is becoming dated? Or are there longstanding product performance issues that you’re failing to gain traction with, where you suspect rheology may hold the answer?
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Biophysical Characterization of Epigenetic Protein Interactions
| By Malvern Instruments
Epigenetics is the study of heritable changes in gene expression caused by nongenetic mechanisms, without alterations in gene structure or DNA sequence. The epigenetic state of a cell evolves during the cellular differentiation and development of an organism, and epigenetic changes are linked to cellular reprogramming. Because epigenetic mechanisms may also be responsible for the integration of environmental responses at he cellular level, they potentially play an important role in the development of som diseases.
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Overcoming and Quantifying 'Wall Slip' in Measurements from a Rotational Rheometer
| By Malvern Instruments
When making shear rheological measurements on structured liquids, in particular suspensions, emulsions or foams there is a high probability that the measurement may be affected by a phenomenon known as 'wall slip'. Wall slip generally results from a localdepletion of the dispersed phase near the geometry walls, effectively forming a lubrication layer at the surface. As a consequence bulk rheological properties are no longer being accurately measured leading to an underestimation of the true viscosity. A similar effect can be observed when measuring solid like materials where there is insufficient friction between the sample and the wall to support the applied stress.
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Preformulation and Stability Studies of Biotherapeutics Using DSC
| By Malvern Instruments
The use of biotherapeutics, such as antibodies and other protein molecules, to treat diseases is a rapidly growing field in the pharmaceutical industry.Biotherapeutics are often required at high concentrations and multiple doses, hence a manufacturer must produce kilogram quantities or more of the protein drug. The manufacturing process for biotherapeutics involves protein expression in thousands of liters of bioreactor medium followed by a purification process using large-scale chromatography columns and filtration systems.
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Protein Storage and Stability Analysis Using the Zetasizer Nano ZSP
| By Malvern Instruments
Spidroins are a unique family of large, structural proteins that make up the bulk of spider silk fibres. The mechanical strength and elasticity of spider silk fibres have led to their successful use in the regeneration of peripheral nerves in rats [1], with the same properties giving the potential for use in a wide range of other applications [2,3,4]. The production of these proteins on an industrial scale, however, has only become possible fairly recently
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Molnar-Institute: Benefits and Capabilities of DryLab®
| By Molnár-Institute
Anybody working in the realm of HPLC who wishes to economize the resources spent developing and running methods can benefit from the advantages offered by DryLab®.
Production & Manufacturing > Manufacturing > White Papers
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