Role of Interconnectivity in Enabling Improved Bioprocess Quality - A Case Study Download our full case study here.
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Facilitating Scale Up: Controlled Stem Cell Cultivation in Stirred Suspension Bioreactors Stem cells have been envisioned as becoming an unlimited cell source for regenerative medicine. However most applications require a large number of stem cells and it is difficult to translate recently applied cultivation methods into the larger scale desired. Stirred suspension bioreactors in particular offer a suitable option. These bioreactors have been successfully introduced at the Hannover Medical School, Germany.
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Replacement of a Phase-Out Technology: Managing Sophisticated Processes With In-Depth Insight Scientists at The Center for Biocatalysis and Bioprocessing (CBB) at the University of Iowa, USA have been carrying out research on bioprocessing technologies for more than 20 years. For the last three years their research has been facilitated by use of the parallel bioreactors described in this article.
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Continuous Monitoring Irrespective of Time and Location The more complex a biotechnology process is, the more difficult it is to predict how the process will proceed. The amounts of data generated are also increasing, driven both by the number of clones being analysed and the process parameters being monitored and controlled. Mobile monitoring of critical process parameters, together with an intelligent information management system, provide an efficient solution.
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Comparative Studies for High Cell Density Fermentation In contract manufacturing one of the most challenging needs is the adaption of proprietary production processes, their optimization as well as process improvements after a transfer from one Contract Manufacturing Organization (CMO) to another. Each single process modification has to be verified with comparable data.
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