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Characterisation of the CMV-Specific CD4 Cell Response

Published 06 May 2014 | By CTL Laboratories

Most humans become infected with HCMV. Typically, the immune system controls the infection, but the virus persists and can reactivate in states of immunodeficiency. While the HCMV-specific CD8 cell and antibody response has been accessible to investigation, studies of the CD4 cell subsets have been limited by the low frequency of the antigen-specific CD4 cells in PBMC.

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Characterisation of the CMV-Specific CD4 Cell Response