Capsugel - Providing Innovative Dosage Forms and Solutions to Health Care Customers

Capsugel is committed to be the leading provider of innovative dosage forms and solutions to healthcare customers around the world.

Capsugel offers a combination of products, equipment and services to provide the pharmaceutical and healthcare industries with comprehensive solutions that meet their formulation and dosage form requirements.

Capsugel offers a complete range of products and services that can be tailored to a customer's specific needs. Capsugel's drug delivery systems provide full flexibility in a number of areas:

• Flexibility of polymer: choose from different polymer options to meet every drug delivery need
• Flexibility of delivery: select special drug delivery systems to allow immediate, modified, sustained or dual release
• Flexibility of dosing: combine APIs in a single capsule for less medication, easier production and better patient compliance
• Flexibility in development: extend the product life cycle by prolonging patent protection through innovative reformulation concepts supported by PDC

Capsules for clinical trials and OTC applications

Thanks to their consistency and reliable performance, Capsugel's two-piece capsules, including hard gelatin, softgel, non-animal, and fish gelatin capsules, have been the product of choice for leading pharmaceutical and healthcare companies for more than a century. Capsugel also offers capsules for specific tasks, such as clinical trials and OTC applications.

Leakproof formulation

Capsugel meets the demanding requirements of liquid, semisolid and lipid drug delivery systems. Unique in the market, Capsugel's liquid-filled capsules are sealed with patented liquid encapsulation microspray sealing LEMS™ technology that guarantees leakproof formulation. Capsugel's softgels cover all sizes, shapes, colors and forms, and are suitable for all types of use.

In addition, Capsugel offers a complete range of services that add value throughout the product lifecycle, such as branding options (colour services, printing), various fillings and sizes. In many situations, the services are tailored to specific customer needs in specific regions of the world.

In line with Capsugel's vision, Capsugel has created a Product Development Center (PDC) to provide pharmaceutical development solutions to their pharmaceutical customers from pre-clinical development to Capsugel's commercial manufacturing. These solutions are centered around Capsugel's technologies, with special emphasis on the Licaps® Drug Delivery System.

The Capsugel Product Development Center has developed a unique, 5-step process to provide the optimal drug delivery system for poorly soluble API, from dosage form development up to commercial manufacturing. PDC's capabilities include formulation services; clinical batches, analytical development and process and scale-up documents.

Capsugel also offers a high-quality line of user-friendly, manual and semi-automated capsule filling machines, backed up by the best service support in the industry.

At Capsugel, quality means people and products working together efficiently and smoothly. Capsugel's Quality Guarantee focuses on these key elements.

• Capsugel capsules are manufactured according to the cGMP guidelines as described in the IPEC guidelines for pharmaceutical excipients
• All Capsugel two-piece gelatin manufacturing facilities are ISO 9001 and 14001 certified
• To ensure the highest quality products and services, Capsugel employs the principles of Six Sigma throughout the entire organisation
• Hard or liquid-filled capsules undergo rigorous tests to make sure they satisfy stringent customer demands
• Continuous state-of-the art in-process monitoring systems further ensure that capsule quality remains consistently high
• Standard Capsugel owned equipment, in combination with globally identical product specifications and control methods, result in identical capsules, wherever they are produced

Contact us to find out more at marketing.emea@pfizer.com or on +33 3 89 20 57 25, or contact your local Capsugel representative.

www.capsugel.com